인간유두종바이러스 감염과 연관된 구강내 편평상피세포암; 문헌고찰 및 증례보고
Oral squamous cell carcinoma associated with human papillomavirus infections; two cases report and review of the literature
변준호, 박봉욱, 이정희, 노규진, 김종렬,
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변준호 ( Byun June-Ho ) - 경상대학교 의학전문대학원 치과학교실 구강악안면외과
박봉욱 ( Park Bong-Wook ) - 경상대학교 의학전문대학원 치과학교실 구강악안면외과
이정희 ( Lee Jeong-Hee ) - 경상대학교 의과대학 병리학교실
노규진 ( Rho Gyu-Jin ) - 경상대학교 수의과대학
김종렬 ( Kim Jong-Ryoul ) - 부산대학교 치의학전문대학원 구강악안면외과학교실
KMID : 0355620070330050548
Abstract
Several investigators have shown that human papillomavirus (HPV) appear to play an etiologic role in oral and paranasal sinus carcinoma. It was known that 15-25 % of head and neck squamous cell carcinoma (SCC) showed HPV-positive infection. Among them, HPV 16 was the most common type but HPV 18 was observed only 2-4 % of HPV-positive head and neck cancers. In recent, we treated uncommon 2 oral SCC cases that associated with HPV infection. One is a case of tongue SCC after bone marrow transplantation (BMT), and the other is a case of SCC occurring with aspergillosis in the maxillary sinus. After surgery, HPV 16 and 18 were detected in the surgical specimens by the histological and polymerase chain reaction (PCR) examination. In this report, we present these cases with a review of literature
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